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多形性脉络膜血管病变的光学相干断层扫描血管造影特征

Srour M, Querques G, Semoun O, et al.

期刊名称:British Journal of Ophthalmology

卷期:2016年第100卷第11期

摘要

目的:旨在分析光学相干断层扫描(OCT-A)下,多发性息肉状脉络膜血管病变(PCV)的形态学特征。方法:包括连续PCV患者的一项前瞻性研究。所有患者均接受完整的眼科检查,包括眼底摄影,荧光素血管造影,吲哚青绿血管造影,光谱域OCTOCT-A。结果:对12例患者(平均年龄72.6±10.5; 4名男性和8名女性)进行了分析。所有眼(12/12)中,OCT-A上显示的脉络膜毛细管分层提示分支血管网络(BVN)。3/12眼(25%)中,OCT-A显示的与息肉状损害相对的脉络膜毛细管分层被低信号晕环绕,9/12眼(75%)中为低涡圆形结构。结论:OCT-A是一种非侵入性成像模式,允许PCV中不同结构的可视化。可连续清楚地检测到BVN OCT-A中显示的息肉状低毛圆形结构可能是由于多形性病变内的异常血流,与BVN形成对比。 OCT-A认识的进一步改善将提供关于PCV中不同强度特征的特异性信息。

Purpose To analyse the morphological characteristics of polypoidal choroidal vasculopathy (PCV) on optical coherence tomography angiography (OCT-A).Methods Prospective study with consecutive patients affected with PCV were included. All patients underwent a complete ophthalmological examination including fundus photography, fluorescein angiography, indocyanine green angiography, spectral-domain OCT and OCT-A.Results Twelve eyes of 12 patients (mean age 72.6±10.5years; 4 men and 8 women) were included for analysis. In all eyes (12/12) the segmentation of the choriocapillaris layer on OCT-A revealed the branching vascular network (BVN) as a hyperflow lesion. OCT-A segmentation of the choriocapillaris layer in correspondence of the polypoidal lesion showed in 3/12 eyes (25%) a hyperflow round structure, surrounded by a hypointense halo, and in 9/12 eyes (75%) a hypoflow round structure.Conclusions The OCT-A is a non-invasive imaging modality allowing the visualisation of different structures in PCV. The BVN is constantly clearly detected. The hypoflow round structure appearance of the polyp in OCT-A, is probably due to an unusual blood flow inside the polypoidal lesions, contrasting with the BVN. Further improvement in OCT-A knowledge will provide information on the specificity of the different intensity characteristics in PCV.


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