SCI TOP 10

当前位置:首页>SCI TOP 10

光学相干层析成像血管造影成像显示的高度近视继发性新生血管形成 NEOVASCULARIZATION SECONDARY TO HIGH MYOPIA IMAGED BY OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY

Bruyère, E., Miere, A., Cohen, S.Y., et al.

期刊名称:Retina

卷期:2017年第37卷第11期

摘要

摘要:目的:旨在描述活动性近视脉络膜新生血管(CNV)的光学相干断层扫描血管造影(OCTA)特征,并比较其与荧光血管造影和光谱域光学相干断层扫描的敏感性。方法:对连续高度近视合并活动性近视性CNV患者进行研究。结果:分析中包括19例表现为初治性CNV和复发性CNV患者的20只眼(平均年龄:59.6±12.1岁,平均等效球镜:-13.5±3.6屈光度) )。 OCTA显示20只眼中有18只近视性CNV,检测敏感度为90%,提示Bruch膜下使用30-μm手动分割可准确显示高流量新生血管网络。OCTA图像上近视性CNV的选择平均面积为0.34±0.45mm,而平均血管面积为0.22±0.27mm。两种新生血管表型在我们的研究病例中为主:血管循环紊乱和组织交错类型。结论:OCTA似乎是检测近视性CNV的一个有价值的高灵敏度工具。然而,其特异性需要进一步研究调查。

PURPOSE:To describe the optical coherence tomography angiography (OCTA) characteristics of active myopic choroidal neovascularization (CNV) and to compare its sensitivity versus fluorescein angiography and spectral-domain optical coherence tomography.METHODS:Consecutive highly myopic patients complicated with active myopic CNV were prospectively included. The OCTA features were analyzed and correlated with the findings of conventional imaging (spectral-domain optical coherence tomography and fluorescein angiography).RESULTS:Twenty eyes of 19 patients (mean age: 59.6 ± 12.1 years, mean spherical equivalent: -13.5 ± 3.6 diopters) presenting with both treatment-naive CNV and recurrent CNV were included in the analysis. The OCTA showed a 90% sensitivity for myopic CNV detection in 18 of 20 eyes, revealing a high-flow neovascular network accurately visible using a 30-μm manual segmentation underneath Bruch membrane. Mean selected area of myopic CNV on OCTA images was 0.34 ± 0.45 mm, whereas the mean vessel area was 0.22 ± 0.27 mm. Two neovascular phenotypes prevailed in our series: disorganized vascular loops and organized interlacing patterns.CONCLUSION:The OCTA seems to be a valuable tool in detecting myopic CNV with a high sensitivity. However, its specificity needs to be investigated in further studies.


点击下载

CopyRight 2016  兴齐100版权所有 京ICP证060955号
技术支持:示剑网络   http://100.sinqi.com/