Li, X., Zarbin, M.A., Langer, P.D., Bhagat, N
摘要：目的：旨在描述眼球开放性损伤后诊断为眼内炎的患者的人口统计学，特征，治疗和视力预后。方法：回顾性队列分析1997 - 2015年间在新泽西州纽瓦克大学医院诊断为眼内炎的所有患者。结果：确定了26只眼（均为男性患者;平均年龄：37±15岁）。16只眼（62％）培养阳性，葡萄球菌（7只眼，44％）是最常见的致病菌。有12只眼（46％）出现开放性眼损伤并发眼内炎; 14只眼（54％）在开放性眼球修复（OGR; 排除1例98天异常病例）后平均14天发生眼内炎。所有眼都进行全身和玻璃体内抗生素治疗。眼内异物（P <0.05）和延迟性原发性OGR（P <0.03）明显较OGR后眼内炎更常见。 OGR后组有4只眼（29％）出现角膜伤口渗漏。没有光感视力的4只眼（15％）被摘除。 25只有最佳矫正视力记录的患者中有10只（40％）的最终矫正视力≥20/ 200;最终的最佳矫正视力从无光感到20/20。结论：眼内异物的存在和延迟表现更常见与眼内炎并发。OGR之后29%的眼内炎眼有伤口渗漏。 40％的病例最终的最佳矫正视力≥20/ 200。
PURPOSE:To describe the demographics, characteristics, management, and visual outcomes of eyes diagnosed with endophthalmitis after open globe injury.METHODS:Retrospective cohort analysis of all patients diagnosed with endophthalmitis after open globe injury from 1997 to 2015 at University Hospital, Newark, NJ.RESULTS:Twenty-six eyes were identified (all male patients; mean age: 37 ± 15 years). Cultures were positive in 16 eyes (62%), with Staphylococcus species (7 eyes, 44%) being the most common organism. Twelve eyes (46%) presented with open globe injury and concurrent endophthalmitis; 14 eyes (54%) developed endophthalmitis a mean of 14 days after open globe repair (OGR; 1 outlier of 98 days excluded). All eyes were managed with systemic and intravitreal antibiotics. The presence of intraocular foreign body (P < 0.05) and delayed primary OGR (P < 0.03) were significantly more common with concurrent versus post-OGR endophthalmitis. Four (29%) eyes in the post-OGR endophthalmitis group had corneal wound leak after OGR. Four (15%) eyes with no light perception vision were enucleated. Ten (40%) of 25 eyes with documented best-corrected visual acuity had final best-corrected visual acuity ≥20/200; final best-corrected visual acuity ranged from no light perception to 20/20.CONCLUSION:The presence of intraocular foreign body and delayed presentation were significantly more common with concurrent endophthalmitis. Twenty-nine percent of eyes that presented with endophthalmitis after OGR had a wound leak. Final best-corrected visual acuity ≥20/200 was achieved in 40% of cases.